GONZALEZ-BELLO, Concepcion: search on Z-Library

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1

β-Lactamase Inhibitors to Restore the Efficacy of Antibiotics against Superbugs

González-Bello, Concepción, Rodríguez, Diana, Pernas, Marina, Rodríguez, Ángela, Colchón, Esther

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 21.39 MB

english, 2019

2

Competitive Inhibitors of Helicobacter pylori Type II Dehydroquinase: Synthesis, Biological Evaluation, and NMR Studies

Cristina Sánchez-Sixto, Verónica F. V. Prazeres, Luis Castedo, Se Won Suh, Heather Lamb, Alastair R. Hawkins, Francisco Javier Cañada, Jesús Jiménez-Barbero, Concepción González-Bello

Journal:

Year:

2008

Language:

english

File:

PDF, 746 KB

english, 2008

3

ChemInform Abstract: Six-Membered Heterocycles: Pyridines

Concepcion Gonzalez-Bello, Luis Castedo

Journal:

Year:

2012

File:

PDF, 18 KB

2012

4

2-Substituted-3-Dehydroquinic Acids as Potent Competitive Inhibitors of Type II Dehydroquinase

Verónica F. V. Prazeres, Luis Castedo, Heather Lamb, Alastair R. Hawkins, Concepción González-Bello

Journal:

Year:

2009

Language:

english

File:

PDF, 538 KB

english, 2009

5

Chiral Aziridination of Olefins Using a Chiral Sulfinamide as the Nitrogen Source

Bonifácio, Vasco, González-Bello, Concepción, Rzepa, Henry, Prabhakar, Sundaresan, Lobo, Ana

Journal:

Year:

2010

Language:

english

File:

PDF, 162 KB

english, 2010

6

Frontispiece: Freezing the Dynamic Gap for Selectivity: Motion-Based Design of Inhibitors of the Shikimate Kinase Enzyme

Prado, Verónica, Lence, Emilio, Thompson, Paul, Hawkins, Alastair R., González-Bello, Concepción

Journal:

Chemistry - A European Journal

Year:

2016

File:

PDF, 2.46 MB

2016

7

QM/MM simulations identify the determinants of catalytic activity differences between type II dehydroquinase enzymes

Lence, Emilio, van der Kamp, Marc W., González-Bello, Concepción, Mulholland, Adrian J.

Journal:

Organic & Biomolecular Chemistry

Year:

2018

Language:

english

File:

PDF, 3.96 MB

english, 2018

8

Photogeneration of Quinone-Methides as Latent Electrophiles for Lysine-Targeting

Perez-Ruiz, Raul, Molins-Molina, Oscar, Lence, Emilio, González-Bello, Concepción, Miranda, Miguel A, Jiménez, M. Consuelo

Journal:

Journal of Organic Chemistry

Year:

2018

Language:

english

File:

PDF, 1.34 MB

english, 2018

9

Synthesis of Rigidified Shikimic Acid Derivatives by Ring-Closing Metathesis to Imprint Inhibitor Efficacy against Shikimate Kinase Enzyme

Pernas, Marina, Blanco, Beatriz, Lence, Emilio, Thompson, Paul, Hawkins, Alastair R, Gonzalez-Bello, Concepcion

Journal:

Organic Chemistry Frontiers

Year:

2019

Language:

english

File:

PDF, 600 KB

english, 2019

10

LN-1-255, a penicillanic acid sulfone able to inhibit the class D carbapenemase OXA-48

Vallejo, Juan A., Martínez-Guitián, Marta, Vázquez-Ucha, Juan C., González-Bello, Concepción, Poza, Margarita, Buynak, John D., Bethel, Christopher R., Bonomo, Robert A., Bou, German, Beceiro, Alejand

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2016

Language:

english

File:

PDF, 624 KB

english, 2016

11

Synthesis of 3-alkyl enol mimics inhibitors of type II dehydroquinase: factors influencing their inhibition potency

Blanco, Beatriz, Sedes, Antía, Peón, Antonio, Lamb, Heather, Hawkins, Alastair R., Castedo, Luis, González-Bello, Concepción

Journal:

Organic & Biomolecular Chemistry

Year:

2012

Language:

english

File:

PDF, 2.80 MB

english, 2012

12

Activity of the β-Lactamase inhibitor LN-1-255 against carbapenem-hydrolyzing class D β-lactamases from Acinetobacter baumannii

Vázquez-Ucha, Juan Carlos, Maneiro, María, Martínez-Guitián, Marta, Buynak, John, Bethel, Christopher R., Bonomo, Robert A., Bou, Germán, Poza, Margarita, González-Bello, Concepción, Beceiro, Alejandr

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2017

Language:

english

File:

PDF, 2.33 MB

english, 2017

13

Self-Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product

Lence, Emilio, Maneiro, MarÃa, Sanz-Gaitero, Marta, van Raaij, MarK J., Thompson, Paul, Hawkins, Alastair R., Gonzalez-Bello, Concepcion

Journal:

Chemistry - A European Journal

Year:

2020

File:

PDF, 1.68 MB

2020

14

Designing Irreversible Inhibitors-Worth the Effort?

González-Bello, Concepción

Journal:

Year:

2016

Language:

english

File:

PDF, 3.85 MB

english, 2016

15

Synthesis of Spiro Carba-Sugars by Ring-Closing Metathesis

Concepción González-Bello, Luis Castedo, Francisco Javier Cañada

Journal:

European Journal of Organic Chemistry

Year:

2006

Language:

english

File:

PDF, 234 KB

english, 2006

16

Synthesis of (2R)-2-bromodehydroquinic acid and (2R)-2-fluorodehydroquinic acid

Manthey, Michael K., González-Bello, Concepción, Abell , Chris

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1997

Language:

english

File:

PDF, 349 KB

english, 1997

17

Reducing the Flexibility of Type II Dehydroquinase Enzyme for Inhibition - A Fragment-Based Approach and Molecular Dynamics Simulation Study

Peón, Antonio, Robles, Adrián, Blanco, Beatriz, Convertino, Marino, Thompson, Paul, Hawkins, Alastair R., Caflisch, Amedeo, Gonzalez-Bello, Concepcion

Journal:

Year:

2017

Language:

english

File:

PDF, 2.24 MB

english, 2017

18

Determination of the Bound Conformation of a Competitive Nanomolar Inhibitor of Mycobacterium tuberculosis Type II Dehydroquinase by NMR Spectroscopy

Verónica F. V. Prazeres, Cristina Sánchez-Sixto, Luis Castedo, Ángeles Canales, Francisco Javier Cañada, Jesús Jiménez-Barbero, Heather Lamb, Alastair R. Hawkins, Concepción González-Bello

Journal:

Year:

2006

Language:

english

File:

PDF, 492 KB

english, 2006

19

Hydrolysis of imidazolidine ligands mediated by CuII: Mononuclear, tetranuclear and 1D CuII-amine complexes

Fondo, Matilde, Doejo, Jesús, García-Deibe, Ana M., Sanmartín, Jesús, González-Bello, Concepción, Vicente, Ramón

Journal:

Year:

2015

Language:

english

File:

PDF, 1.39 MB

english, 2015

20

Inhibition of Helicobacter pylori and Its Associated Urease by Palmatine: Investigation on the Potential Mechanism

Zhou, Jiang-Tao, Li, Cai-Lan, Tan, Li-Hua, Xu, Yi-Fei, Liu, Yu-Hong, Mo, Zhi-Zhun, Dou, Yao-Xing, Su, Rui, Su, Zi-Ren, Huang, Ping, Xie, Jian-Hui, Gonzalez-Bello, Concepción

Journal:

Year:

2017

Language:

english

File:

PDF, 3.45 MB

english, 2017

21

Hydroxylammonium derivatives for selective active-site lysine modification in the anti-virulence bacterial target DHQ1 enzyme

Maneiro, María, Lence, Emilio, Sanz-Gaitero, Marta, Otero, José M., van Raaij, Mark J., Thompson, Paul, Hawkins, Alastair R., González-Bello, Concepción

Journal:

Organic Chemistry Frontiers

Year:

2019

File:

PDF, 3.42 MB

2019

22

ChemInform Abstract: Synthesis of 4-Deoxyquinic, 4-Deoxyshikimic and 4-Deoxy-3-dehydroshikimic Acid.

Concepcion Gonzalez-Bello, John R. Coggins, Alastair R. Hawkins, Chris Abell

Journal:

Year:

1999

File:

PDF, 25 KB

1999

23

A Novel Pathway of Protein Haptenation by ß-Lactams

Jiménez, M. Consuelo, Pérez-Ruiz, Raúl, Lence, Emilio, Andreu, Inmaculada, González-Bello, Concepción, Miranda, Miguel A., Limones-Herrero, Daniel

Journal:

Chemistry - A European Journal

Year:

2017

Language:

english

File:

PDF, 2.02 MB

english, 2017

24

Irreversible covalent modification of type I dehydroquinase with a stable Schiff base

Tizón, Lorena, Maneiro, María, Peón, Antonio, Otero, José M., Lence, Emilio, Poza, Sergio, van Raaij, Mark J., Thompson, Paul, Hawkins, Alastair R., González-Bello, Concepción

Journal:

Organic & Biomolecular Chemistry

Year:

2015

Language:

english

File:

PDF, 1.97 MB

english, 2015

25

Specific chemical modification of bacterial type I dehydroquinase – opportunities for drug discovery

González-Bello, Concepción

Journal:

Future Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 2.96 MB

english, 2015

26

Synthesis of Amino Carba Sugars and Conformationally Restricted Polyhydroxy γ-Amino Acids from (−)-Quinic Acid

Montserrat Carballido, Luis Castedo, Concepción González-Bello

Journal:

European Journal of Organic Chemistry

Year:

2004

Language:

english

File:

PDF, 151 KB

english, 2004

27

Chemical Modification of a Dehydratase Enzyme Involved in Bacterial Virulence by an Ammonium Derivative: Evidence of its Active Site Covalent Adduct

González-Bello, Concepción, Tizón, Lorena, Lence, Emilio, Otero, José M., van Raaij, Mark J., Martinez-Guitian, Marta, Beceiro, Alejandro, Thompson, Paul, Hawkins, Alastair R.

Journal:

Journal of the American Chemical Society

Year:

2015

Language:

english

File:

PDF, 1.24 MB

english, 2015

28

Recently developed synthetic compounds with anti-infective activity

González-Bello, Concepción

Journal:

Current Opinion in Pharmacology

Year:

2019

File:

PDF, 556 KB

2019

29

Functional desymmetrization of 1,3-dioximes for the obtention of 1,2,3-hetero trisubstituted carbocycles

Valdemar B.C. Figueira, Arantxa G. Esqué, Ravi Varala, Concepción González-Bello, Sundaresan Prabhakar, Ana M. Lobo

Journal:

Tetrahedron Letters

Year:

2010

Language:

english

File:

PDF, 233 KB

english, 2010

30

Recently developed synthetic compounds with anti-infective activity

González-Bello, Concepción

Journal:

Current Opinion in Pharmacology

Year:

2019

Language:

english

File:

PDF, 556 KB

english, 2019

31

Challenging antimicrobial susceptibility and evolution of resistance (OXA-681) during treatment of a Pseudomonas aeruginosa ST175 clone long-term nosocomial infection

Arca-Suárez, Jorge, Fraile-Ribot, Pablo, Vázquez-Ucha, Juan Carlos, Cabot, Gabriel, Martínez-Guitián, Marta, Lence, Emilio, González-Bello, Concepción, Beceiro, Alejandro, Rodríguez-Iglesias, Manuel,

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2019

Language:

english

File:

PDF, 573 KB

english, 2019

32

Investigation of metabolite-protein interactions by transient absorption spectroscopy and in silico methods

Limones-Herrero, Daniel, Palumbo, Fabrizio, Vendrell-Criado, Victoria, Andreu, Inmaculada, Lence, Emilio, González-Bello, Concepción, Miranda, Miguel A., Jiménez, M. Consuelo

Journal:

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy

Year:

2020

File:

PDF, 1.99 MB

2020

33

Progress in type II dehydroquinase inhibitors: From concept to practice

Concepción González-Bello, Luis Castedo

Journal:

Medicinal Research Reviews

Year:

2007

Language:

english

File:

PDF, 1.09 MB

english, 2007

34

Metal-Assisted Ring-Closing/Opening Process of a Chiral Tetrahydroquinazoline

García-Deibe, Ana M., Sanmartín-Matalobos, Jesús, González-Bello, Concepción, Lence, Emilio, Portela-García, Cristina, Martínez-Rodríguez, Luis, Fondo, Matilde

Journal:

Inorganic Chemistry

Year:

2012

Language:

english

File:

PDF, 4.94 MB

english, 2012

35

ChemInform Abstract: Designing Irreversible Inhibitors - Worth the Effort?

Gonzalez-Bello, Concepcion

Journal:

Year:

2016

File:

PDF, 16 KB

2016

36

Freezing the Dynamic Gap for Selectivity: Motion-Based Design of Inhibitors of the Shikimate Kinase Enzyme

Prado, Verónica, Lence, Emilio, Thompson, Paul, Hawkins, Alastair R., González-Bello, Concepción

Journal:

Chemistry - A European Journal

Year:

2016

Language:

english

File:

PDF, 11.19 MB

english, 2016

37

Antibiotic Adjuvants – A Strategy to Unlock Bacterial Resistance to Antibiotics

González-Bello, Concepción

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

38

Comparative Binding Energy (COMBINE) Analysis for Understanding the Binding Determinants of Type II Dehydroquinase Inhibitors

Peón, Antonio, Coderch, Claire, Gago, Federico, González-Bello, Concepción

Journal:

Year:

2013

Language:

english

File:

PDF, 940 KB

english, 2013

39

Photobinding of Triflusal to Human Serum Albumin Investigated by Fluorescence, Proteomic Analysis, and Computational Studies

Molins-Molina, Oscar, Pérez-Ruiz, Raúl, Lence, Emilio, González-Bello, Concepción, Miranda, Miguel A., Jiménez, M. Consuelo

Journal:

Frontiers in Pharmacology

Year:

2019

Language:

english

File:

PDF, 2.52 MB

english, 2019

40

The conformational rigidity of butane-1,2-diacetals as a powerful synthetic tool

Lence, Emilio, Castedo, Luis, González-Bello, Concepción

Journal:

Chemical Society Reviews

Year:

2008

Language:

english

File:

PDF, 1.08 MB

english, 2008

41

Editorial [ The Medicinal Chemistry of Anti-Infectious Agents Guest Editor: Concepcion Gonzalez-Bello ]

Gonzalez-Bello, Concepcion

Journal:

Current Topics in Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 12 KB

english, 2008

42

Stereoselective Synthesis of Novel Cyclic γ-Amino Acids and Triazole Derivatives

Verónica F. V. Prazeres, Luis Castedo, Concepción González-Bello

Journal:

European Journal of Organic Chemistry

Year:

2008

Language:

english

File:

PDF, 487 KB

english, 2008

43

A selective resin for trans-diequatorial-1,2-diols

Emilio Lence, Luis Castedo, Concepción González-Bello

Journal:

Tetrahedron Letters

Year:

2009

Language:

english

File:

PDF, 560 KB

english, 2009

44

Mycobacterium tuberculosis Shikimate Kinase Inhibitors: Design and Simulation Studies of the Catalytic Turnover

Blanco, Beatriz, Prado, Verónica, Lence, Emilio, Otero, José M., Garcia-Doval, Carmela, van Raaij, Mark J., Llamas-Saiz, Antonio L., Lamb, Heather, Hawkins, Alastair R., González-Bello, Concepción

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 1.49 MB

english, 2013

45

Using Surface Enhanced Raman Scattering to Analyze the Interactions of Protein Receptors with Bacterial Quorum Sensing Modulators

Costas, Celina, López-Puente, Vanesa, Bodelón, Gustavo, González-Bello, Concepción, Pérez-Juste, Jorge, Pastoriza-Santos, Isabel, Liz-Marzán, Luis M.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.72 MB

english, 2015

46

Study of the Phosphoryl-Transfer Mechanism of Shikimate Kinase by NMR Spectroscopy

Prado, Verónica, Lence, Emilio, Vallejo, Juan A., Beceiro, Alejandro, Thompson, Paul, Hawkins, Alastair R., González-Bello, Concepción

Journal:

Chemistry - A European Journal

Year:

2016

Language:

english

File:

PDF, 5.71 MB

english, 2016

47

Cover Picture: Nanomolar Competitive Inhibitors of Mycobacterium tuberculosis and Streptomyces coelicolor Type II Dehydroquinase (ChemMedChem 2/2007)

Verónica F. V. Prazeres, Cristina Sánchez-Sixto, Luis Castedo, Heather Lamb, Alastair R. Hawkins, Alan Riboldi-Tunnicliffe, John R. Coggins, Adrian J. Lapthorn, Concepción González-Bello

Journal:

Year:

2007

File:

PDF, 43 KB

2007

48

Parallel Solid-Phase Synthesis and Evaluation of Inhibitors of Streptomyces c oelicolor Type II Dehydroquinase

González-Bello, Concepción, Lence, Emilio, Toscano, Miguel D., Castedo, Luis, Coggins, John R., Abell, Chris

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 331 KB

english, 2003

49

Targeting the Motion of Shikimate Kinase: Development of Competitive Inhibitors that Stabilize an Inactive Open Conformation of the Enzyme

Prado, Verónica, Lence, Emilio, Maneiro, María, Vázquez-Ucha, Juan C., Beceiro, Alejandro, Thompson, Paul, Hawkins, Alastair R., González-Bello, Concepción

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 2.03 MB

english, 2016

50

Synthesis of 4-deoxyquinic, 4-deoxyshikimic and 4-deoxy-3-dehydroshikimic acids

González-Bello, Concepción, Coggins, John R., Hawkins, Alastair R., Abell, Chris

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1999

Language:

english

File:

PDF, 176 KB

english, 1999

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